Disorder due to hormone deficiency & excess.

Disorders due to hormone deficiency (Hyposecretion)

Name of disorder	Hyposecretion of	Symptoms
1.       Acromicria (in adults)	Somatotrophin	Bones of the face and extremities are small and delicate.
2.       Addison’s disease	Aldosterone	Hypertension, dizziness, vomiting, diarrhea, low blood sugar, low plasma Na+, high plasma K+, increased urinary Na+ and bronze like pigmentation of skin.
3.       Cretinism (in children)	Thyroxin	Retarded growth, low intelligence, delayed sexual maturity.
4.       Diabetes insipidus	Vasopressin (ADH)	Enormous secretion of urine (polyuria), excess thirst (polydypsia) etc
5.       Diabetes mellitus	Insulin	Hyperglycemia (high sugar level in blood), glycosuria (sugar in urine), polyphagia (overeating), polydypsia (excess thirst) and polyuria (frequent urination).
6.       Dwarfism	Somatotrophin	Short in stature.
7.       Myxoedema (in adults)	Thyroxin	Physical sluggishness, mental dullness, low metabolic rate, dry and coarse skin and puffy face.
8.       Tetany	Parathormone (PTH)	Steep drop in blood calcium level, abnormal rise in excitability of nerves and muscles, sustained and violent contraction of muscles of face, larynx, hands and feet.
9.       Eunuchoidism	Testosterone	Lack male secondary sexual characters, sterility etc

Disorders due to excess hormone (Hypersecretion)

Name of disorder	Hypersecretion of	Symptoms
1.       Acromegaly (in adults)	Somatotrophin	Abnormal growth of bones of face, lower jaw, hands and feet. Enlargement of internal organs such as lungs, spleen etc
2.       Adrenal virilism (in female)	Sex corticoid	Masculanization of females such as growth of beards and moustaches and male voice etc.
3.       Conn’s syndrome	Aldosterone	Headache, Excessive urination at night, Excessive thirst, Excessive urination, Increased volume of blood, Increased blood sodium level, High alkalinity of blood and body fluids,
4.       Cushing’s syndrome	Cortisol	High blood sugar, obesity, deposition of fat in the face, neck etc. rise in plasma Na+ and high BP. In acute condition it leads to mental depression and impotency.
5.       Exophthalmic goiter (Grave’s disease)	Thyroxin	Hypertrophy of thyroid gland, increased metabolism, high rate of heartbeat, bulging eyeballs, restlessness, nervousness and loss of weight.
6.       Gigantism (in children)	Somatotrophin	Excessive height, extreme bone, muscle and organ growth.
7.       Hyperglycaemia	Glucagon	Polyphagia, Polydipsia, Polyuria, Blurred vision, Fatigue (sleepiness), Weight loss Poor wound healing (cuts, scrapes, etc.), Dry mouth, Dry or itchy skin, Tingling in feet or heels, Erectile dysfunction, Recurrent infections, external ear infections (swimmer's ear), Cardiac arrhythmia, Stupor, Coma, Seizures
8.       Insulin shock	Insulin	Abnormal lowering of blood glucose (hypoglycemia), sudden fall of body temperature, fatigue, tremors and unconsciousness.
9.       Kidney stone	Parathormone	Accumulation of calcium in blood and it precipitate with phosphates to form kidney stones.
10.     Osteitis fibrosa cystica	Parathormone	Calcification of soft tissues like blood vessels