Photosensitization/
Photosensitizational Dermatitis
Photosensitization is the allergic
reaction of the skin to light due to the presence of photodynamic agents
(originated from certain drugs, plants or other substances).
Host:
Ø Human,
Ø Cattle,
Ø Sheep,
Ø Goat,
Ø Pig and
Ø Horse.
Clinical Signs
Ø Burning or itching sensation,
Ø Erythema,
Ø Inflammatory edema,
Ø The skin may be necrotic and may
slough off within few days in severe cases,
Ø Affected areas of animals are- teat,
udder, perineum,
Ø In sheep, muzzle, head and ears are
affected and this head is called ‘Big head’ in South Africa and ‘Facial Eczema’
in New Zealand,
Ø In horse, face, lower portion of
limbs and unpigmented skin are mostly affected,
Ø Healing or gangrene and death may
occur.
Conditions required for Photosensitization
Ø Direct sunlight,
Ø Photodynamic substance in circulation
and
Ø Unpigmented area of the body.
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